MS Microbiome Study

Part of an international study testing whether gut bacteria play a role in multiple sclerosis.

Condition(s)

  • Multiple sclerosis

About the project

The Anne Rowling Clinic is taking part in an international study of gut bacteria and their potential role in developing multiple sclerosis. The study is called the International MS Microbiome Study (iMSMS).

We all have millions of bacteria living inside us. This study compares the bacteria (microbiome) present in people with and without MS. We could learn which bacteria are needed to restore a healthy balance, which may lead to new MS treatments based on diet. Early evidence suggests bacteria in the gut may influence whether a person develops MS and the potential disease course. If we can learn more about which bacteria are involved, we could potentially influence the disease course or even ultimately prevent MS developing.

You may be able to take part if you have been diagnosed with MS and have somebody living with you who is willing to pair up with you. Participants have a single study visit where they complete questionnaires, have a clinical examination and give a blood sample. You will also be asked to provide a stool sample at home after the visit which you can post directly to our laboratories using a pre-prepared pack.

Download the iMSMS patient information leaflet v3 [PDF]

Find out more on the iMSMS study website.

Funder(s)

The global iMSMS Consortium is led by Professors Stephen Hauser and Sergio Baranzini from the Department of Neurology, University of California, San Francisco (UCSF). The UK arm of the study is funded by the Anne Rowling Clinic.

Publication(s)

N/A

Status

Recruiting now

Contact

Microbiome Research Nurse
denise.cranley1@nhs.net
0131 465 9517

Eligibility criteria

People with MS may be eligible if they:

  • are at least 18 years old
  • are not on steroids or antibiotics or had any gastro infections recently
  • have no confirmed diagnosis of any other autoimmune disease or chronic infectious disease
  • have someone living with them who is willing to participate in the study as a control
  • willing and able to provide a blood and stool sample

If you are a control for somebody with MS you may be eligible if you:

  • are at least 18 years old
  • are not on steroids or antibiotics or had any gastro infections recently
  • have no confirmed diagnosis of any other autoimmune disease or chronic infectious disease
  • willing and able to provide a blood and stool sample


photo credit: image_jungle/Getty Images

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