Biotin is a vitamin that is normally present in food and is needed for energy production in cells. It could also help with myelin repair. In previous studies, it was shown that the use of biotin at high doses (300 mg/day, which corresponds to 10,000 times the amount usually present in the average diet) may slow the progression of clinical signs in participants with progressive MS.
The study involves 11 visits to the Anne Rowling Clinic over 28 months. The study visits will include a physical examination, blood test, questionnaires and ECG (heart tracing). Participants will get a 50/50 chance of being on the investigational drug or placebo. Part way through the trial, all participants will have the opportunity to take the investigational drug.
