International MS Microbiome Study

Could gut bacteria play a role in MS?

Condition(s)

  • Multiple sclerosis

Project type

  • Understanding the condition

About the project

The International Microbiome MS research study is looking at the role of gut bacteria in people living with multiple sclerosis (MS).

We all have millions of bacteria living inside us. This important international study compares the bacteria (microbiome) present in people with and without MS.

Why is it important?

Early evidence suggests bacteria in the gut may influence whether a person develops MS and the potential disease course.

What could we learn?

We could learn which bacteria are needed to restore a healthy balance, which may lead to new MS treatments. 

What can you do?

You may be able to take part if you have been diagnosed with MS and have somebody living with you who is willing to pair-up with you. You can phone and speak to one of the microbiome research team on 0131 465 9517, or speak with your MS specialist nurse.

What is involved?

Participants have a single study visit where they complete questionnaires, have a clinical examination, and give a blood sample. You will also be asked to provide a stool sample at home after the visit which you can post directly to our laboratories using a pre-prepared pack.

Related links

Read the scientific article: "Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and course". iMSMS Consortium. Cell, 2022. DOI: doi.org/10.1016/j.cell.2022.08.021. Only the summary is free of charge at this link. For an unformatted version of the full text please visit the page for this output on Edinburgh Research Explorer.

International Multiple Sclerosis Microbiome Study (iMSMS) website

Anne Rowling Clinic MS Microbiome study page

About multiple sclerosis

Funder(s)

The global iMSMS Consortium is led by Professors Stephen Hauser and Sergio Baranzini from the Department of Neurology, University of California, San Francisco (UCSF). The UK arm of the study is funded by the Anne Rowling Clinic.

Publication(s)

Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and course
iMSMS Consortium.
2022 Sep 15 in
Cell
DOI: 10.1016/j.cell.2022.08.021

Status

Recruiting now

Contact

Microbiome Research Team
anne.rowling.clinic@ed.ac.uk
0131 465 9517

Eligibility criteria

Diagnosis of multiple sclerosis (MS).

Other criteria apply please get in touch to find out more.


photo credit: image_jungle/Getty Images

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