ROPAD Study
A global observational study focusing on the role of genetics in Parkinson's.
Condition(s)
- Parkinson’s & movement disorders
Project type
- Understanding the condition
About the project
The Rostock International Parkinson's Disease Study (ROPAD), is a global observational study focusing on the role of genetics in the cause and progression of Parkinson's.
Alongside clinical information, the study involves a simple blood test (which can be taken at home) for DNA and biomarker analysis.
Genetic analysis will begin with GBA and LRRK2, two genes in which specific clinical trials for mutation carriers are being planned in the next few years. If no mutations are identified, a comprehensive analysis of other PD associated genes will be performed to identify novel genetic variants.
Funder(s)
Centogene
Publication(s)
The Rostock International Parkinson's Disease (ROPAD) Study: Protocol and Initial Findings
Volha Skrahina PhD, Hanaa Gaber, Eva-Juliane Vollstedt, Toni M. Förster et al
2020 Dec 14 in Movement Disorders - Official Journal of the International Parkinson and Movement Disorders Society
Status
Closed – analysing data
Contact
Dr David Breen
david.breen@nhs.scot
Eligibility criteria
Dr Breen's Parkinson's clinic patients only