The STARTUP trial: Tibial nerve stimulation

A study to see if electrical stimulation applied to the lower leg relieves bladder problems in people with Parkinson's.


  • Parkinson’s & movement disorders

Project type

  • Understanding the condition

About the project

Bladder problems are common in people with Parkinson’s. This includes having to go to the toilet frequently and urgently, especially during the night, sometimes leading to urine leakage (incontinence).

These symptoms impact significantly on people's quality of life and unfortunately, there are few treatment options to help with these symptoms. Transcutaneous tibial nerve stimulation, also called TTNS, is a treatment which has helped many men and women to reduce their bladder problems. However, this treatment has not been tested in people with Parkinson’s. This study is investigating if TTNS helps people with Parkinson’s who have bother with their bladder.


Parkinson's UK & Dunhill Medical Trust



Closed – analysing data


Dr Gordon Duncan

Eligibility criteria

Anyone with a confirmed diagnosis of Parkinson's who has urinary frequency. 


Image credit: IrKiev/GettyImages