We are pleased to share that a recent study led by our colleagues Dr Rozanna Meijboom, Dr Peter Foley and Professor Adam Waldman, "Fatigue in early multiple sclerosis: MRI metrics of neuroinflammation, relapse and neurodegeneration" (Meijboom et al. 2024), has been the focus of a commentary by Professor Lauren Krupp, published in Brain Communications.
Professor Krupp is an internationally recognised leader in fatigue and multiple sclerosis (MS) and in her commentary emphasises the relevance of the study’s findings to the ongoing effort to understand MS-related fatigue, one of the most common yet complex symptoms of the disease.
In their study, Dr Rozanna Meijboom and colleagues present findings from the large, longitudinal, multi-centre FutureMS study, led by the Anne Rowling Clinic. Their results show that, in people newly diagnosed with multiple sclerosis, fatigue cannot be readily linked to structural imaging measures of inflammation or neurodegeneration.
Professor Krupp’s commentary highlights how these findings are a helpful addition to our understanding of fatigue and remind us of the complexity and heterogeneity of this individual experience.
Further reading
Read the commentary in the Brains Communication journal: Fatigue in multiple sclerosis: still elusive after all these years (external website)
Read the original study published in the Brains Communications journal: Fatigue in early multiple sclerosis: MRI metrics of neuroinflammation, relapse and neurodegeneration (external website)
Useful links
Profile for Dr Rozanna Meijboom
Profile for Dr Peter Foley
Profile for Prof Adam Waldman
Profile for Prof Lauren B Krupp (New York University, Langone Health, external website)
Find a research project: a listing of research studies at the Anne Rowling Clinic filterable by disease and status.
Image courtesy of Dr Rozanna Meijboom